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a- (1)

prefix or inseparable particle, a conglomerate of various Germanic and Latin elements.
In words derived from Old English, it commonly represents Old English an "on, in, into" (see on (prep.)), as in aliveaboveasleepabackabroadafootashoreaheadabedaside, obsolete arank "in rank and file," etc., forming adjectives and adverbs from nouns, with the notion "in, at; engaged in." In this use it is identical to a (2).
It also can represent Middle English of (prep.) "off, from," as in anewafreshakinabreast. Or it can be a reduced form of the Old English past participle prefix ge-, as in aware.
Or it can be the Old English intensive a-, originally ar- (cognate with German er- and probably implying originally "motion away from"), as in abideariseawakeashamed, marking a verb as momentary, a single event. Such words sometimes were refashioned in early modern English as though the prefix were Latin (accursedallayaffright are examples).
In words from Romanic languages, often it represents reduced forms of Latin ad "to, toward; for" (see ad-), or ab "from, away, off" (see ab-); both of which by about 7c. had been reduced to a in the ancestor of Old French. In a few cases it represents Latin ex.
[I]t naturally happened that all these
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a- (2)

word-forming element meaning "away," from Latin a "off, of, away from," the usual form of Latin ab before consonants (see ab-). As in avertavocation. It is also the a in a priori and the à in Thomas à KempisThomas à Becket.

a- (3)

prefix meaning "not, without," from Greek a-an- "not" (the "alpha privative"), from PIE root *ne- "not" (source also of English un-).
In words from Greek, such as abysmaladamantamethyst; also partly nativized as a prefix of negation (asexualamoralagnostic). The ancient alpha privatum, denoting want or absence.
Greek also had an alpha copulativuma- or ha-, expressing union or likeness, which is the a- expressing "together" in acolyteacousticAdelphi, etc. It is from PIE root *sem- (1) "one; as one, together with."
 
📙后缀丨-a📘单词丨Aa